Longevity & BioregulatorsUpdated July 2, 2026 · Educational reference

What Is Prostamax? Dosage, Half-Life & How to Track It

Also known as: Lys-Glu-Asp-Pro · KEDP · Khavinson prostate bioregulator

ClassLongevity bioregulator (Lys-Glu-Asp-Pro tetrapeptide)
Typical dose500 mcg–1 mg daily (8-wk titration)
Half-lifeNot established — no published human PK data
Typical routeIntramuscular, once daily
Target tissueProstate
Quick answer

Prostamax is a synthetic tetrapeptide (Lys-Glu-Asp-Pro, or KEDP) studied for effects on prostate tissue. Unlike most peptides in this family it is dosed intramuscularly, once daily, titrating from 500 mcg up to 1 mg over about eight weeks — mirroring the 15–60-day daily-IM schedules used in the preclinical studies it is based on. The evidence is animal and cell-based, not human trials. Educational information only.

What Prostamax is and how it works

Prostamax is a synthetic tetrapeptide with the sequence Lys-Glu-Asp-Pro (KEDP), developed out of research into a prostate tissue peptide complex. It is part of the same Khavinson bioregulator family as the other short peptides on this list, but tissue-targeted toward the prostate specifically.

The proposed mechanism is the same epigenetic story that runs through this whole peptide class: short chains like KEDP are theorized to interact with chromatin and histones, modulating which genes a target tissue expresses, rather than binding a receptor the way a conventional drug does.

The research behind Prostamax is preclinical — the daily intramuscular dosing convention traces back to animal studies run over 15–60 days, not a human clinical trial. It is not FDA-approved, and there is no controlled human data on its effects on the prostate.

Typical dosing & reconstitution

Prostamax is reconstituted with bacteriostatic water — a 20 mg vial mixed with 2.0 mL gives 10 mg/mL, where one U-100 unit equals 100 mcg (0.1 mg).

Unlike most bioregulators on this list, the studied route is intramuscular, not subcutaneous:

PhaseDaily doseUnits (U-100)
Weeks 1–2500 mcg5 units
Weeks 3–4750 mcg7.5 units
Weeks 5–81,000 mcg10 units
Weeks 9–12 (optional)1,000 mcg10 units

That mirrors the 15–60-day daily-IM window used in the preclinical research it is modeled on — the 12-week option is an extension some protocols add, not something derived from new data.

Half-life & what it means for frequency

No published pharmacokinetic study has measured how long Prostamax stays active in the body. The once-daily IM schedule matches how it was administered in the underlying preclinical work, not a calculated clearance rate.

That also explains the route choice: intramuscular injection was simply what the source studies used. There's no data comparing it against a subcutaneous version, so switching routes on your own is an unverified deviation from the only protocol that has any evidence behind it at all.

What to track & possible side effects

There is no dedicated human tolerability study for Prostamax — what exists is preclinical, and it doesn't speak meaningfully to side effects in a person. Standard sterile-injection and sourcing precautions apply, and IM injections in particular call for correct site technique to avoid nerve or vascular injury.

What's actually worth tracking here is simple: dose, day, and whatever prostate-health marker motivated trying it — logged consistently enough that an 8–12-week protocol produces something you can look back on.

How to track Prostamax in Stackeddd

Prostamax is one of the few bioregulators dosed IM rather than subcutaneously — log the route along with the dose so an 8-week protocol stays consistent. Get the reconstitution numbers right first: at 10 mg/mL, unit-to-mg math is easy to get wrong by eye.

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Reconstitution Calculator

Model it yourself: enter your vial size and BAC water and the Peptides tab returns concentration and exact units for any dose — the same math built into the Stackeddd app.

Related compounds

Related reading: Peptide reconstitution math: how much BAC water to add

Frequently asked questions

What is Prostamax?

Prostamax is a synthetic tetrapeptide (Lys-Glu-Asp-Pro, or KEDP) studied for effects on prostate tissue, developed out of prostate-tissue peptide complex research. It is not FDA-approved, and the evidence behind it is preclinical.

What is Prostamax used for?

It is studied for prostate-tissue-targeted effects, theorized to work through epigenetic interactions with chromatin and histones that modulate gene expression. There is no human clinical trial data confirming an effect on prostate health.

How is Prostamax dosed?

Protocols use intramuscular injection once daily, titrating from 500 mcg to a 1 mg maintenance dose over about eight weeks, mirroring the 15–60-day daily-IM schedules used in the preclinical studies it draws from.

Why is Prostamax injected intramuscularly instead of subcutaneously like other bioregulators?

Because that is the route used in the preclinical research the protocol is based on. There is no comparative data on a subcutaneous version, so the IM route reflects what was actually studied rather than a general rule for this peptide class.

This is educational information, not medical advice. Doses and protocols above reflect published references and community practice — protocol decisions belong with your prescribing physician. Generic names used throughout. How this reference is built & how the AI is tested →

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