What Is Vilon? Dosage, Half-Life & How to Track It
Also known as: Lys-Glu · KE dipeptide · Khavinson thymus bioregulator
Vilon is the shortest of the Khavinson bioregulators — a two-amino-acid peptide (Lys-Glu) studied for immune-system effects. Unlike the other bioregulators here, it is dosed in a pulsed pattern: once daily for 5 consecutive days, then a rest period, repeated monthly, ramping from 67 mcg up to 333–667 mcg per injection. Evidence is preclinical cell-culture work. Educational information only.
What Vilon is and how it works
Vilon is a synthetic dipeptide — just two amino acids, lysine and glutamic acid (Lys-Glu) — making it the shortest compound in the Khavinson bioregulator family. It is studied for immunoregulatory effects rather than the anti-aging or organ-specific targets of its longer relatives.
Preclinical research reports that Vilon may enhance immune markers, including CD5+ lymphocytes and interleukin-2 (IL-2) expression, in thymic and splenic cell cultures — both signals tied to immune-cell activity and maturation. That points toward the thymus, the organ where immune cells mature, as the working hypothesis for where it acts.
This is cell-culture data, not a human immune-function trial. Vilon is not FDA-approved, and there is no clinical study measuring its effect on immune markers, infection rates, or anything else in people.
Typical dosing & reconstitution
Vilon is reconstituted with bacteriostatic water — a 20 mg vial mixed with 3.0 mL gives roughly 6.67 mg/mL, where one U-100 unit is about 66.7 mcg.
Its dosing pattern is different from the rest of this list: pulsed, not continuous — five consecutive days of injections, then a rest period, repeated monthly:
| Cycle / day | Daily dose | Units (U-100) |
|---|---|---|
| Cycle 1, Day 1 | 67 mcg | 1 unit |
| Cycle 1, Day 2 | 133 mcg | 2 units |
| Cycle 1, Day 3 | 200 mcg | 3 units |
| Cycle 1, Day 4 | 267 mcg | 4 units |
| Cycle 1, Day 5 | 333 mcg | 5 units |
| Cycle 2+ (Days 1–5) | 333–667 mcg | 5–10 units |
After Day 5, the protocol calls for a rest period through the remainder of a 4-week cycle before repeating — this is a pulsed regimen, not a daily-forever one.
Half-life & what it means for frequency
There is no published half-life for Vilon. The pulsed 5-days-on, then-rest structure isn't derived from pharmacokinetic clearance data — it mirrors the cycling pattern used in the preclinical studies behind it, which tested repeated short courses rather than continuous dosing.
That makes Vilon the one bioregulator on this list where the schedule itself — which day of which cycle you're on — is the whole ballgame. Miss the pattern and you're not running the protocol that has any research behind it.
What to track & possible side effects
Human tolerability data doesn't exist for Vilon beyond what's incidentally reported in the underlying cell-culture research. Because the proposed mechanism touches the immune system, an active immune condition or autoimmune history is a reasonable reason to talk to a doctor before starting.
Reconstituted Vilon also has a shorter usable window than most bioregulators here — use within about a week, or aliquot and freeze — so what to track includes the vial's mix date, not just the dose. Given the pulsed schedule, logging exactly which cycle day you're on is the difference between following the protocol and drifting off it.
How to track Vilon in Stackeddd
Vilon's 5-days-on, rest-of-the-month-off pattern is easy to lose track of by month two — log each cycle day so you always know where you are, and note your reconstitution date since the mixed vial doesn't keep as long as most bioregulators. Confirm the units first: the dose changes every single day for the first five.
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Reconstitution Calculator
Model it yourself: enter your vial size and BAC water and the Peptides tab returns concentration and exact units for any dose — the same math built into the Stackeddd app.
Related compounds
Related reading: Peptide reconstitution math: how much BAC water to add
Frequently asked questions
What is Vilon?
Vilon is a synthetic dipeptide (Lys-Glu) — the shortest of the Khavinson bioregulators — studied for immunoregulatory effects tied to the thymus. It is not FDA-approved, and the evidence behind it is preclinical.
What is Vilon used for?
Preclinical research reports increased CD5+ lymphocyte markers and IL-2 expression in thymic and splenic cell cultures, suggesting immune-modulating effects. There is no human trial confirming this in people.
How is Vilon dosed?
Unlike most bioregulators, Vilon uses a pulsed schedule: once daily for 5 consecutive days, ramping from 67 mcg to 333 mcg, then a rest period for the remainder of a 4-week cycle. Later cycles run 333–667 mcg per day for the same 5-day window.
How long does reconstituted Vilon last?
Protocols recommend using it within about a week of reconstitution, or aliquoting and freezing what you won't use — shorter than the roughly two-week window given for some other bioregulators on this list.
This is educational information, not medical advice. Doses and protocols above reflect published references and community practice — protocol decisions belong with your prescribing physician. Generic names used throughout. How this reference is built & how the AI is tested →
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